Enantioselective photocatalytic synthesis of bicyclo[2.1.1]hexanes as ortho-disubstituted benzene bioisosteres with improved biological activity

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dc.contributor.affiliation000000041762408X
dc.contributor.affiliationOrganic Chemistry Department, Faculty of Science, Autonomous University of Madrid, Madrid, Spain; IMDEA Nanociencia, Madrid, Spain; Organic Chemistry Department, Faculty of Chemical Sciences, Complutense University of Madrid, Madrid, Spain; Organic Chemistry Department, Faculty of Optics and Optometry, Complutense University of Madrid, Madrid, Spain; Center of Innovation in Advanced Chemistry (ORFEO-CINQA), Madrid, Spain; Institute for Advanced Research in Chemical Sciences (IAdChem), Autonomous University of Madrid, Madrid, Spainen
dc.contributor.authorGarrido-García P.
dc.contributor.authorQuirós I.
dc.contributor.authorMilán-Rois P.
dc.contributor.authorOrtega-Gutiérrez S.
dc.contributor.authorMartín-Fontecha M.
dc.contributor.authorCampos L.A.
dc.contributor.authorSomoza, Álvaro
dc.contributor.authorFernández I.
dc.contributor.authorRigotti T.
dc.contributor.authorTortosa M.
dc.date.accessioned2025-03-20T09:47:11Z
dc.date.available2025-03-20T09:47:11Z
dc.date.issued2025
dc.identifier.doi10.1038/s41557-025-01746-7en
dc.identifier.urihttps://hdl.handle.net/20.500.12614/3943
dc.issue.number5608en
dc.journal.titleNature Chemistryen
dc.language.isoenen
dc.relation.projectIDTEMPMinisterio de Ciencia, Innovación y Universidades, MCIU; Spanish Association Against Cancer; IMDEA; Fundación Científica Asociación Española Contra el Cáncer, AECC; European Commission, EC; Agencia Estatal de Investigación, AEI, (PID2023-146982OB-I00, PID2022-138797OB-I00, RED2022-134331-T, PID2022-142594NB-I00, PID2022-139318NB-I00, PID2020-119352RB-I00); Agencia Estatal de Investigación, AEI; Spanish ‘Severo Ochoa’ Programme for Centres of Excellence in R&D, (CEX2020-001039-S); European Research Council, ERC, (101002715); European Research Council, ERC; Marie Curie, (101151954); Marie Curie
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.titleEnantioselective photocatalytic synthesis of bicyclo[2.1.1]hexanes as ortho-disubstituted benzene bioisosteres with improved biological activityen
dc.typeresearch articleen

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