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Actin reorganization at the centrosomal area and the immune synapse regulates polarized secretory traffic of multivesicular bodies in T lymphocytes

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dc.contributor.affiliation"Department of Metabolism and Cell Signaling, Instituto De Investigaciones Biomédicas Alberto Sols. CSIC-UAM, Madrid, Spain"," UAM, Departamento De Bioquímica. Facultad De Medicina, Madrid, Spain"," Centro De Biología Molecular Severo Ochoa, Universidad Autónoma De Madrid, Cantoblanco, Madrid, Spain"," Nanostructured Functional Surfaces Program, IMDEA Nanociencia, Universidad Autónoma De Madrid, Cantoblanco, Madrid, Spain"," Neuroimmunology Unit, Puerta De Hierro-Segovia De Arana Health Research Institute, Madrid, Spain"," Imperial College London, South Kensington Campus, National Heart & Lung Institute, Faculty of Medicine, London, United Kingdom"," Central Laser Facility, Science and Technology Facilities Council, UK Research and Innovation. Research Complex at Harwell, Harwell-Oxford, United Kingdom"en
dc.contributor.affiliation000000041762408X
dc.contributor.authorBello-Gamboa A.
dc.contributor.authorVelasco M.
dc.contributor.authorMoreno S.
dc.contributor.authorHerranz G.
dc.contributor.authorIlie R.
dc.contributor.authorHuetos S.
dc.contributor.authorDávila S.
dc.contributor.authorSánchez A.
dc.contributor.authorBernardino De La Serna J.
dc.contributor.authorCalvo V.
dc.contributor.authorIzquierdo M.
dc.date.accessioned2020-12-04T15:12:06Z
dc.date.available2020-12-04T15:12:06Z
dc.date.issued2020
dc.format.mimetypeapplication/pdf
dc.identifier.doi10.1080/20013078.2020.1759926
dc.identifier.urihttp://hdl.handle.net/20.500.12614/1479
dc.issue.number1759926
dc.journal.titleJournal of Extracellular Vesicles
dc.language.isoen
dc.relation.projectIDTEMPWe are indebted and acknowledge Dr D.D. Billadeau (Mayo Clinic, USA) for generous sharing of shFMNL1 and FMNL1 isoform rescue constructions. We acknowledge the excellent technical support from A. Sánchez and A. Garrido. We acknowledge Dr A. Anel (Universidad de Zaragoza, Spain) for suggestions and critical reading of this manuscript and Dr M.A. Alonso (CBM, CSIC) for reagents and scientific advice. Thanks to D. Morales (SIDI-UAM) and S. Gutiérrez (CNB, CSIC) for their superb expertise with confocal microscopy. This work was supported by grants from the Spanish Ministerio de Economía y Competitividad (MINECO), Plan Nacional de Investigación Científica (SAF2016-77561-R to M.I., which was in part granted with FEDER-EC funding).
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.titleActin reorganization at the centrosomal area and the immune synapse regulates polarized secretory traffic of multivesicular bodies in T lymphocytes
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number9
dspace.entity.typePublication

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