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Ultrafast folding kinetics of WW domains reveal how the amino acid sequence determines the speed limit to protein folding

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dc.contributor.affiliation"Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, Madrid, 28040, Spain"," Departamento de Química Física e Instituto de Biotecnología, Facultad de Ciencias, Universidad de Granada, Granada, 18071, Spain"," Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Campus de Cantoblanco, Madrid, 28049, Spain"," Department of Bioengineering, School of Engineering, University of California, Merced, CA 95343, United States"," Center for Cellular and Biomolecular Machines, University of California, Merced, CA 95343, United States"," Nanobiosystems Programme, Instituto Madrileño de Estudios Avanzados Nanociencia, Madrid, 28049, Spain"en
dc.contributor.affiliation000000041762408X
dc.contributor.authorSzczepaniak M.
dc.contributor.authorIglesias-Bexiga M.
dc.contributor.authorCerminara M.
dc.contributor.authorSadqi M.
dc.contributor.authorde Medina C.S.
dc.contributor.authorMartinez J.C.
dc.contributor.authorLuque I.
dc.contributor.authorMuñoz V.
dc.date.accessioned2020-12-04T16:44:56Z
dc.date.available2020-12-04T16:44:56Z
dc.date.issued2019
dc.identifier.doi10.1073/pnas.1900203116en
dc.identifier.urihttp://hdl.handle.net/20.500.12614/1799
dc.journal.titleProceedings of the National Academy of Sciences of the United States of Americaen
dc.language.isoenen
dc.page.initial8137en
dc.relation.projectIDinfo:eu:eu-repo/grantAgreement/EC/FP7/323059/EU/Downhill Folding Protein Modules as Conformational Rheostats: Roles in Molecular Biology and Applications as Biosensors/MOLRHEOSTATen
dc.relation.projectIDTEMPACKNOWLEDGMENTS. This research has been funded by Grant ERC-2012-ADG-323059 from the European Research Council and Grant NSF-MCB-1616759 from the National Science Foundation. V.M. also acknowledges support from the W. M. Keck Foundation and the Center for Cellular and Biomolecular Machines at University of California, Merced (Grant NSF-CREST-1547848). I.L. acknowledges support from the Spanish Ministry of Science and Education through Grants BIO2012-39922-CO2-01 and BIO2016-787746-C2-1-R, and the European Union through Fonds Européen de Développement Économique et Régional.
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.rights.accessRightsopen accessen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.titleUltrafast folding kinetics of WW domains reveal how the amino acid sequence determines the speed limit to protein foldingen
dc.typeresearch articleen
dc.volume.number116en
dspace.entity.typePublication

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